What’s in a Name? Frances Oldham Kelsey and the Power of Skepticism

If Dr. Frances Oldham Kelsey had been named Mary, Helen, or Dorothy, it’s possible that thousands of babies would have died or been born with debilitating birth defects.

In the mid-1930s, after earning a master’s degree in pharmacology in her native Canada, Frances Oldham wrote to Eugene Geiling, a researcher at the University of Chicago, asking to work in his lab and study for a doctorate. Assuming Frances was a man, Dr. Geiling replied with an offer of a scholarship, addressing the letter to “Mr. Oldham.”


Dr. Kelsey upends the stereotype of the government bureaucrat. She saved lives by being a stickler for details.


Reflecting on the incident in an autobiography, she remembered Dr. Geiling as a “very conservative and old-fashioned” man who “did not hold too much with women as scientists.” His assumption that Frances Oldham was male might have played a role in her scholarship and subsequent education, which prepared her for a career that touched every American.

From an Early Victory in Chicago to a New Career in Washington, D.C.

After moving to Chicago, Frances Oldham earned a doctorate in pharmacology in 1938 and a medical degree in 1950. Along the way, she got married, becoming Dr. Frances Oldham Kelsey, and gave birth to two daughters.

Her work in Dr. Geiling’s lab provided early experience in unraveling medical mysteries. In 1937, more than 100 people, including 34 children, died after taking a liquid sulfa drug formulated with an artificial fruit flavor. Dr. Geiling’s team of scientists soon identified the problem: The medicine was composed primarily of antifreeze — along with the active ingredient, coloring, and flavorings. It was sent to market with no testing. Public outrage led to the 1938 passage of the Food, Drug, and Cosmetic Act, which required manufacturers to provide evidence to the FDA that their drugs were safe. Continue reading

Over 90 Percent of What Planned Parenthood Does, Part 23: Preconception Counseling for a Healthy, Informed Pregnancy

Welcome to the latest installment of “Over 90 Percent of What Planned Parenthood Does,” a series on Planned Parenthood Advocates of Arizona’s blog that highlights Planned Parenthood’s diverse array of services — the ones Jon Kyl never knew about.

pregnancyFew moments in life are as important and complex as when a woman makes the decision of whether and when to have children. There are many considerations to take into account when planning to conceive, many of which can affect not only the baby, but the mother as well.

Preconception counseling, a service of Planned Parenthood Arizona, can provide those who wish to conceive with valuable information about their own health, suggestions about how to best manage their wellness for pregnancy, and education about a range of outcomes (including the possibility of miscarriage). Preconception counseling can assist you in creating an environment focused on optimal health for both you and your future child.

These counseling services include:

  • targeted medical history with focus on teratogenic exposures, ethnic background, and family history
  • social history with focus on risk factors for sexually transmitted diseases (STDs), tobacco, alcohol, and street drug use
  • history of chronic illnesses
  • physical exam
  • labs as indicated (STDs, diabetes screening, etc.)
  • genetic counseling referrals as indicated
  • immunization review
  • folic acid utilization
  • review of current medications and possible hazardous exposures

The above list might seem long and detailed, but upon closer examination, you might not know what all of these things mean. What are teratogenic exposures? What does folic acid have to do with a healthy pregnancy? Let’s look at some of these topics in more depth. Continue reading