STD Awareness: Eliminating HPV-Related Cancers

Earlier this month, every major cancer center and organization in the country released a joint statement calling for the elimination of cervical cancer, along with all other HPV-related cancers. The elimination of a large swath of cancers might sound like a tall order — so far, we’ve only eradicated two viruses from the planet: smallpox and rinderpest. And we’re on the brink of getting rid of a third, the virus that causes polio.

But doing away with human papillomavirus (HPV) would herald a new chapter in disease eradication, because HPV causes cancer, meaning that eradicating HPV will eradicate the cancers caused by it. And the good news is we have all the tools we need to wipe HPV off the face of the earth — we just need to use them.


The tools to wipe a large class of cancers off the face of the earth are right under our noses — we just have to use them.


A quick rundown on HPV is in order. It’s the most common sexually transmitted infection in the world, and causes multiple cancers — cervical, head and neck, anal, vulvar, vaginal, and penile. While it’s most well-known for causing cervical cancer, here in the United States it is transitioning away from its old job, causing more head-and-neck cancers than cervical cancers. Nearly all sexually active people will be infected with HPV at least once in their lives, and though only a fraction of infections progress to cancer, its ubiquity means it still causes hundreds of thousands of cancers every year. In the United States, around 41,000 HPV-related cancers are diagnosed annually, while more than 600,000 are diagnosed worldwide. Continue reading

For the Safety of Students: Five Questions for Mary Koss

Mary P. Koss, Ph.D.

With close to 300 peer-reviewed publications and a number of academic awards to her name, it’s hard to believe that University of Arizona Regents’ Professor Mary P. Koss once had to fight her way into the doctoral program in psychology at the University of Minnesota. Her test scores put her head and shoulders above other applicants, but it took a tense meeting with the department head — in which she let a bit of profanity slip out — to finally get accepted into their graduate school. Clinical psychology was a very male-dominated field in the early 1980s, when she was starting her career, and that was all too clear when a colleague shared his idea for a study that would explore male undergraduates’ attitudes toward rape — by having models pose in varying sizes of padded bras and be rated for their desirability and culpability if raped.


The term date rape was first used in the news media 35 years ago this month.


From that conversation, though, came the seed of an idea that would soon set Dr. Koss apart from her peers. At that time, Dr. Koss was at Kent State in Ohio, still years before she joined the University of Arizona. She made a name for herself studying campus sexual assault by developing a survey that revolutionized efforts to gauge respondents’ experiences of sexual aggression and victimization, revealing a higher prevalence than previously thought. Her initial study was publicized 35 years ago this month, in Ms. Magazine’s September 1982 issue, in an article that also marked the first time a national news publication used the term date rape. Both Dr. Koss’ research and the introduction of that term to the national conversation were game-changers in many ways.

At the time the article was published, most rape-prevention programs on college campuses were relatively new and narrowly focused on the danger posed by strangers — the assailants waiting in alleyways, rather than the familiar faces in classrooms or dorms. Dr. Koss’ research, as well as the stories writer Karen Barrett reported from Stanford University and the University of Connecticut for the Ms. article, revealed that many cases of rape, especially those committed by the victims’ peers and acquaintances, were often ignored, denied, or misunderstood as something other than rape. The concept of date rape helped many people recognize rape — their own or others’ — that had been perpetrated by people known to the victims.

Greater awareness and understanding of the problem of campus sexual assault soon followed, but the 35 years since then have seen both progress and setbacks. In fact, as the anniversary of that historic Ms. article approached, news began coming from the Department of Education that Secretary of Education Betsy DeVos vowed to revisit Obama-era policies that addressed campus sexual assault. A series of information-gathering meetings included a group that, according to the Southern Poverty Law Center, seeks “to roll back services for victims of domestic abuse and penalties for their tormentors.” Continue reading

STD Awareness: Is Gonorrhea Becoming “Impossible” to Treat?

Image: National Institute of Allergy and Infectious Disease

Health authorities have been worried about it for a long time now, and we’ve been following it on our blog since 2012. The boogeyman? Antibiotic-resistant gonorrhea, a strain of the sexually transmitted bacteria that is becoming more and more difficult to treat. Higher doses of the drug will be needed to cure stubborn cases of gonorrhea — until the doses can no longer be increased. Then, untreatable gonorrhea could be a reality.


“Little now stands between us and untreatable gonorrhea.”


The World Health Organization (WHO), in a press release last month, finally used the word “impossible” when describing treatment of antibiotic-resistant gonorrhea, referring to documented cases of gonorrhea that were “untreatable by all known antibiotics.” Worse, these cases are thought to be the proverbial “tip of the iceberg,” as there aren’t good data on antibiotic-resistant gonorrhea in many developing countries, where gonorrhea is more prevalent and epidemics could be spreading under the radar. Adding to this problem is the fact that gonorrhea rates are climbing worldwide, which is thought to be due to a number of factors, including the decline in condom use, the frequent absence of symptoms, inadequate treatment, and increasing urbanization and travel.

What will happen if gonorrhea can’t be cured? Your infection could clear up on its own, after a lengthy battle with your immune system, but we don’t know a lot about how long this could take (weeks? months? never?). Unfortunately, despite your immune system’s best efforts, gonorrhea doesn’t go out without a fight. Gonorrhea can lead to pelvic inflammatory disease, which can cause tissue damage to the reproductive organs resulting in infertility, ectopic pregnancy, and chronic pain. It can also cause scarring that blocks sperm’s movement out of the testes, resulting in epididymitis, which is associated with infertility, chronic scrotal pain, and testicular shrinkage. Furthermore, gonorrhea increases risk for HIV transmission and can be passed to a baby during childbirth. The CDC estimates that, in the United States alone, untreatable gonorrhea could cause 75,000 cases of pelvic inflammatory disease, 15,000 cases of epididymitis, and 222 extra HIV infections over a 10-year period. Worldwide, where gonorrhea and HIV disproportionately affect developing countries, these problems could get even more out of control. Continue reading