Tag Archives: immune globulin

Why Do Newborns Need the Hepatitis B Vaccine?

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The first vaccine a baby receives — within hours or days of birth — protects them from hepatitis B virus (HBV). In a lot of people’s minds, HBV is associated with drug use and sexual activity — which stigmatizes people who have been infected with HBV or are carriers of the virus. Unfortunately, this stigma causes a lot of people to question why babies even need to be vaccinated against it, often pointing to “Big Pharma” conspiracy theories. A lot of other people are put off by the misconception that the HBV vaccine is made with human blood (it’s not).

May is Hepatitis Awareness Month, a time to learn about a childhood vaccine that’s saved millions of lives.

There are perfectly good reasons to vaccinate babies against HBV, mainly that HBV is the leading cause of liver cancer, itself one of the Top 10 types of cancer worldwide. Nine out of 10 infants born to a mother who is an HBV carrier will develop chronic infections and become carriers themselves — and a quarter of them will die prematurely of liver disease. Babies who develop chronic HBV infections are 63 times more likely to develop liver cancer than non-carriers, a connection that is 2 to 3 times stronger than the link between smoking and lung cancer.

When it comes to HBV, age at infection matters. Most people with chronic HBV infections are exposed at birth or in early childhood, when they are most likely to develop chronic, lifelong infections — whereas only 2 to 6 percent of infected adults will develop chronic infections, with only 15 percent of them eventually dying from liver disease. The fact that chronic infection risk is inversely correlated with age at infection means that birth is the time when a child is the most vulnerable to this virus — hence the importance of vaccinating as early as possible. Continue reading →

Hepatitis B Vaccine: The Importance of the Birth Dose

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babiesDid you know that Saturday kicked off National Infant Immunization Week, which is part of a worldwide observance that shines the spotlight on the importance of vaccination? Most of us think of infant immunization as a tool to protect babies from childhood illnesses like chickenpox and whooping cough. But did you know that one infant immunization protects them from cancer later in life?

Globally, hepatitis B virus (HBV) is one of the top causes of cancer. Every year, it kills more than three-quarters of a million people worldwide. An HBV infection might be defeated by the immune system, but when it’s not, it can become a chronic infection. And chronic infections can lead to serious health outcomes, including cirrhosis and liver cancer. The younger you are, the less likely you’ll be able to fight off an HBV infection — 90 percent of infants infected with HBV will develop chronic infections, and 25 percent of them will go on to die prematurely after developing liver disease. Compare that to 2 to 6 percent of infected adults who will develop chronic infections.

Because infants are so vulnerable to developing chronic infections, vaccinating them against hepatitis B at birth makes sense.

Most people think of hepatitis as a bloodborne disease, and it is spread very efficiently when IV drug users share needles, during needle-stick accidents and other occupational injuries, or by using contaminated piercing needles, tattoo equipment, or acupuncture needles. Even sharing items like razors, toothbrushes, and nail clippers can do it, as the virus can survive outside of the human body for a week. HBV can also be spread by sexual contact, including vaginal and anal sex.

Lastly, babies and children can be at risk as the virus can be transmitted from mother to infant during birth, and during early childhood when risk of chronic infection is high. A significant number of people with chronic infections acquired them during early childhood, but we don’t know exactly how they got them, as their parents and other household contacts were negative for the virus or its antibodies. Since infants and children are at the highest risk for developing chronic infections, focusing on that population for prevention is very important.

Luckily, there’s a vaccine. Continue reading →

STD Awareness: Sexually Transmitted Diseases and Pregnancy

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Every month since January 2011, we’ve been sharing installments of our STD Awareness series, and each month, we’ve encouraged you to protect yourself from sexually transmitted diseases (STDs) by using dental dams and condoms. But what if you’re trying to get pregnant? In that case, you’re probably not using condoms! However, it is very important that partners know their STD status — being screened and treated for STDs prior to pregnancy is a good idea for your health, and can protect your future baby.

If you and a partner are trying to get pregnant, you might consider being screened for STDs together.

When present during pregnancy, certain STDs can have negative health effects for you or your future baby (including preterm labor, stillbirth, low birth weight, pneumonia, certain infections, blindness, and liver disease), especially if they are not cured or treated in time. Receiving prenatal care can help prevent these problems, so it is important to be screened and treated for STDs prior to or early in your pregnancy.

During pregnancy, the immune system undergoes changes, which are probably necessary to ensure that the body doesn’t reject the fetus — normally, the immune system recognizes non-self cells as potential pathogens and attacks. These immune system changes might make a pregnant person more susceptible to disease. Latent viral infections, like genital warts or herpes, might come out of dormancy. Additionally, anatomical changes lead to a larger exposed area of the cervix, which is potentially more vulnerable to initial infections. Continue reading →