STD Awareness: Can Gene Editing Cure HIV?

For the first time in history, someone with HIV has been treated with cells edited in the lab. It was a bold attempt to try to replicate previous successes in “curing” HIV through bone marrow transplants, but the results were a mixed bag.

Your DNA is like a book, and each sentence is a gene. Imagine a word is misspelled. Sometimes, a misspelling won’t affect your ability to understand the sentence, but other times, it will be so bad that you’ll have trouble figuring out the intended meaning. Think of the difference between “I drive a car” and “I driv a car,” or “I like food” and “I like flod.” You might not be able to tell what that last sentence is even trying to say! Those misspellings are mutations, and sometimes mutations are relatively benign (“I driv a car”), while other times they can cause diseases (“I like flod”).


A mutated version of the CCR5 gene confers near-immunity to HIV — but increases susceptibility to other viruses.


CRISPR, pronounced crisper, is a powerful new technology that can edit genes. By cutting DNA at a specific location and replacing some of the letters in the genetic alphabet, CRISPR can edit genes like you can edit a document using “find and replace.” The hope is that, someday, CRISPR could be used to fight disease by tweaking faulty genes. Continue reading

A Conversation With Faye Wattleton: Part 3, Family Planning and Race

Faye Wattleton (left) with Maxine Waters and Jesse Jackson, 1992

Faye Wattleton was president of Planned Parenthood Federation of America from 1978 to 1992. She was generous enough to speak to me on January 7, 2013, and throughout the month of February we’ll be sharing her experiences and perspectives in observance of Black History Month. This third installment covers questions of racism, especially as aimed at Planned Parenthood and its founder, Margaret Sanger.

Faye Wattleton is clear that women’s autonomy is at the core of the reproductive rights debate. Her philosophy regarding the struggle for reproductive rights, as she said during our interview, “gradually evolved to the conclusion that this is still really about the fundamental right and values that women are held to. That our reproduction is still a proxy for the larger question of our full status as human beings and as citizens.” The question is whether the government will seize the power to make decisions about women’s bodies.


“Racism has a very deep vein in this country and our culture.”


Ms. Wattleton, as the first African American president of Planned Parenthood Federation of America, was often asked how she could work for an organization founded by Margaret Sanger, a woman who allegedly saw birth control as a tool to eradicate the Negro race, to use the language of Sanger’s time. For example, when Ms. Wattleton debated Randall Terry, founder of Operation Rescue, on the Phil Donahue Show in 1991, he accused her of being a traitor to her race by working for Planned Parenthood: “Margaret Sanger … wanted to eliminate the black community,” Terry said to Ms. Wattleton. “You have been bought.”

Ms. Wattleton responded, “I do not need you to tell me what my choices are about my life and my body because I am a black person. I can make that choice for myself, just as every black woman can make that choice for herself.” Reflecting further on Margaret Sanger during our conversation, Ms. Wattleton added, “I could never understand why Margaret Sanger was hauled out. Maybe she was racist. George Washington had slaves. What am I supposed to do? Give up my American citizenship for that?” Continue reading