Tag Archives: adverse reactions

STD Awareness: Does Gardasil Have Side Effects?

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Teen_GroupIn 2006, a vaccine called Gardasil made its debut. Its ability to protect against two of the most widespread strains of human papillomavirus (HPV) means that it doesn’t just protect against an infectious disease — it protects against cancer, too. A persistent HPV infection can trigger cell changes that could lead to cancers of the mouth, throat, cervix, vulva, anus, or penis. Gardasil also protects against two additional strains of HPV that cause most genital warts.

The most common Gardasil side effects are fainting, dizziness, nausea, headache, fever, and hives, as well as possible pain, redness, or swelling at the injection site.

Cervical cancer is not as common in the developed world as it once was, thanks to an effective screening test. The Pap test catches “precancerous” cell changes, allowing the precancer to be treated before it develops into full-fledged cancer. So, while HPV vaccines have the potential to save hundreds of thousands of lives if they can be distributed in countries without widespread access to Pap testing, they have utility in the United States, too. Gardasil has spurred declines in high-risk HPV infections and genital wart incidence among American girls — which means less “precancer” and all the invasive, possibly expensive or painful, treatments that they entail, and a lot fewer genital warts. What’s not to like about that?

Despite this, a lot of people are curious about Gardasil’s side effects. If you enter a few key search terms into Google, you can easily find all kinds of websites warning you of Gardasil’s alleged dangers. So, you might be wondering: Is Gardasil safe?

What are Gardasil’s side effects?

Despite Gardasil’s relatively recent debut, many studies have already been conducted to evaluate its safety — and research continues so that we can consistently reassess its risks and benefits. So far, the consensus is that Gardasil is safe, with very few side effects. According to the Centers for Disease Control and Prevention, the most common Gardasil side effects are fainting, dizziness, nausea, headache, fever, and hives, as well as possible pain, redness, or swelling at the injection site. These reactions are not considered to be serious, some people don’t experience any of them, and they are only temporary. Continue reading →

Gardasil and Mortality

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womenVaccination is one of public health’s greatest achievements, but today’s sociopolitical climate promotes unfounded fears. In turn, this fear-mongering has led to outbreaks of otherwise rare infectious diseases, such as measles and whooping cough. Human papillomavirus (HPV) vaccines protect against two HPV strains that cause 70 percent of cervical cancers, which itself is the second-most common type of cancer in women worldwide. Immunization has the potential to eliminate these viral strains, which would save lives and reduce health care costs — but, unfortunately, vaccine horror stories are a dime a dozen on the Internet, and HPV vaccines like Gardasil are popular targets for vaccine opponents.

Of 57 million Gardasil doses given in the United States, 40 confirmed deaths have occurred in recipients. However, these deaths were not caused by vaccination.

There are many claims flying around that Gardasil causes serious side effects, including death. However, claims that Gardasil can lead to death aren’t supported by good evidence. Generally speaking, people who make these accusations obtain their information from a publicly accessible database called the Vaccine Adverse Event Reporting System (VAERS), which collects claims of adverse events from anyone — including health care providers, patients, or family members.

What is an adverse event?

Most people don’t realize that the phrase “adverse event” cannot be used interchangeably with the term “side effect.” An adverse event is something that occurs after a vaccination — such as a headache, seizure, depression, or death. It could happen one second after being injected with a vaccine or more than a year afterward. It could be a coincidence, or it might be caused by vaccination. For example, if two weeks after receiving a flu shot I get a headache, I could legitimately claim it is an “adverse event,” even if my headache had nothing to do with the shot. An adverse event is only called a side effect if it is found to have been caused by vaccination.

What is VAERS?

Despite its occasional misrepresentation in print media, social media, and the blogosphere, VAERS is not a source of information about verified side effects — it is a database of adverse events that have been self-reported by the public. Anyone can submit a report to VAERS — heck, I could claim that the flu shot gave me telekinetic powers in addition to that headache, and it would be recorded in the database. That doesn’t mean that you should worry about coming down with a nasty case of telekinesis after getting a flu shot at the corner drug store. Continue reading →

Gardasil and Fertility

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girlsThere is currently a lot of fear about vaccines out there, and if you pay attention to the news, you’ve probably caught a whiff of it. This panic was launched by a 1998 Lancet article authored by Andrew Wakefield, who claimed that the MMR vaccine causes autism. Much ink was spilled unpacking that fiasco, but, in a nutshell, Wakefield falsified data and conducted unethical, invasive procedures on children, and was consequently stripped of his medical license. Researchers couldn’t duplicate his findings, The Lancet retracted his article, and Wakefield was thoroughly discredited.

One case report asserting a link between Gardasil and premature ovarian failure was authored by an anti-abortion activist.

But vaccine fears still linger. For example, there are some scary stories floating around about Gardasil, the vaccine that protects against the four most common strains of human papillomavirus (HPV), the sexually transmitted virus that can cause genital warts or certain types of cancer. These stories include claims that it has caused premature ovarian failure leading to infertility. About 57 million doses of HPV vaccines have been given in the United States, however, and in such a large group there are going to be some unexplained phenomena. Without good evidence, we can’t jump to the conclusion that a vaccine caused them.

According to the Centers for Disease Control and Prevention, the most common Gardasil side effects are fainting; dizziness; nausea; headache; fever; hives; and pain, redness, or swelling at the injection site. These reactions aren’t considered to be serious, most people don’t experience any of them, and they’re only temporary. However, while surfing the Internet or scrolling through your Facebook wall, you might have come across claims that Gardasil causes infertility — specifically, premature ovarian failure in girls and young women. What should you make of these horror stories?

A couple of medical journals have described unexplained ovarian failure in four patients who also received HPV vaccines. Medical journals publish many kinds of articles, and a “case report” is a description of one or a few patients’ experiences. Unlike an article that summarizes the results of a rigorous scientific study involving hundreds or thousands of subjects, a case report might just highlight an unusual situation. They aren’t considered to be sources of “definitive” statements about much of anything. Nevertheless, in 90 percent of patients with premature ovarian failure, doctors can’t find clear genetic or physiological causes for the condition, making it an interesting topic for a medical journal to cover — and ripe for speculation. Continue reading →

Over 90 Percent of What Planned Parenthood Does, Part 15: Fertility Awareness Education

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Welcome to the latest installment of “Over 90 Percent of What Planned Parenthood Does,” a series on Planned Parenthood Advocates of Arizona’s blog that highlights Planned Parenthood’s diverse array of services — the ones Jon Kyl never knew about.

Fertility awareness is not the same as the rhythm method.

Let’s start there.

It’s a common misconception that is, at best, a massive oversimplification that misconstrues the concept and may lead people to dismiss or deride fertility awareness out of hand. In reality, a lot of people could benefit from a more thorough understanding of fertility, as many sexually active couples spend a lot of their lives trying to control it — whether to avoid or achieve pregnancy. Planned Parenthood health centers provide education in fertility awareness-based methods (FAMs) for a variety of purposes.

If fertility awareness is not just the rhythm method, what is fertility awareness?

For someone having menstrual cycles, fertility awareness involves monitoring cycle signs and symptoms — predominantly cervical fluid and basal body temperature, though these are often supported or “cross referenced” by tracking other signs as well — in order to determine when a person is approaching ovulation and/or to confirm when ovulation has already taken place.

How does that even work?

Fertility awareness-based methods rely on a few underlying assumptions about fertility and the likelihood of conception:

  1. For pregnancy to happen, there must be both sperm and an ovum (egg) present.
  2. Ovulation — the release of an egg from the ovary into the fallopian tube — occurs once per menstrual cycle.
  3. Sperm can survive inside someone with a uterus for approximately five to six days. (Note: The actual number a given person or couple will want to use for this assumption can vary a bit depending on whether their main goal is to achieve or avoid pregnancy.)
  4. The ovum itself is viable in the fallopian tube for approximately one to two days. After that, it begins to disintegrate, and fertilization is not possible during that cycle. (Again, different couples may use different assumptions depending on their goals.) Continue reading →

HPV Vaccines: Separating Fiction from Fact

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Gardasil is one of two HPV vaccines. It protects against two cancer-causing strains of HPV and two wart-causing strains.

You’ve probably heard a lot about the HPV vaccine, which protects against the sexually transmitted pathogen human papillomavirus — which itself can lead to cancers of the cervix, anus, throat, and more. Unfortunately, there is a lot of misinformation about the vaccine, such as Michele Bachmann’s debunked claim that it causes mental retardation. But, even before Bachmann gave us her two cents, there have been plenty of falsehoods flying around about the HPV vaccine.

Myth: Vaccination against HPV will increase sexual promiscuity among vaccine recipients.

Fact: Studies show that this fear is unfounded.

A study published this month in the American Journal of Preventive Medicine contradicts this claim. In a group of more than 4,000 young females, there was no significant difference between the vaccinated and the unvaccinated in terms of number of sexual partners or the age at which sexual activity began.

Together, HPV-16 and HPV-18 cause about 70 percent of cervical cancers.

Besides, the vast majority of teenagers who choose abstinence do so for reasons other than a fear of contracting HPV. Additionally, HPV is one of many sexually transmitted diseases (STDs); if fear of contracting an STD were the only factor in teenagers’ celibacy, a vaccine that protected against only one STD would not remove this fear.

(It might bear pointing out that when the HPV vaccine was approved for boys and men, fears about male promiscuity didn’t seem to run as rampant.)

Myth: Because the HPV vaccine only protects against two cancer-causing strains of HPV, it isn’t useful in cancer prevention.

Fact: The two cancer-causing strains of HPV that the vaccine protects against account for 70 percent of all cases of cervical cancer. Furthermore, Gardasil protects against two additional strains of HPV, which together are responsible for 90 percent of genital warts. Continue reading →